co q10 coenzyme Q-10 supplement

Coenzyme Q10 ( co-q-10 )

Coenzyme Q (CoQ),

also known as ubiquinone or ubiquinol, is a biologically active quinone with an isoprenoid side chain, related in structure to vitamin K and vitamin E.
Coenzyme Q was first discovered by professor Fred L. Crane and colleagues at the University of Wisconsin Enzyme Institute. In 1958, its chemical structure was reported by Dr. D.E. Wolf and a research group at Merck Laboratories led by Dr. Karl Folkers

Because of its ability to transfer electrons and therefore act as an antioxidant, Coenzyme Q has become a valued dietary supplement. CoQ10 has been widely used for the treatment of heart disease (especially heart failure), gum diseases, and also breast cancer. Young people are able to make Q10 from the lower numbered ubiquinones such as Q6 or Q8. The sick and elderly may not be able to make enough, thus Q10 becomes a vitamin later in life and in illness.

Supplementation of Coenzyme Q10 has been found to have a beneficial effect on the condition of some sufferers of migraine headaches, and is a common component of the "mito cocktail" used to treat mitochondrial disorders and other metabolic disorders. It is also being investigated as a treatment for cancer, and as relief from cancer treatment side effects.

Recent studies have shown that the antioxidant properties of Coenzyme Q10 benefit the body and the brain in animal models. Some of these studies indicate that Coenzyme Q10 protects the brain from neurodegenerative disease such as Parkinsons and also from the damaging side effects of a transient ischemic attack (stroke)in the brain. Another recent study shows a survival benefit after cardiac arrest if coenzyme Q10 is administered in addition to commencing active cooling (to 32–34 degrees Celsius).





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coenzyme q10  
Coenzyme Q-number.

co-Q10 is a Nootropic drug

Nootropics, popularly referred to as "smart drugs", are substances which boost human cognitive abilities (the functions and capacities of the brain). The word nootropic is derived from the Greek words noos or "mind" and tropein meaning "to bend/turn." Typically, nootropics are alleged to work by increasing the brain's supply of neurochemicals (neurotransmitters, enzymes, and hormones), by improving the brain's oxygen supply, or by stimulating nerve growth.

Note that cardiovascular exercise [1] performed on a regular basis also has nootropic effects, by increasing the body's capacity to supply brain cells with oxygen. Exercise is highly synergistic with nutritional supplementation, and a health regimen is incomplete without it.

Some other OTC Nootropic supplements.

Nicotinic acid (vitamin B3) - Essential nutrient. Mild enhancer of concentration and memory. Vasodilator. Mood stabilizer, with a powerful anti-anxiety effect — perhaps the best and most immediate stress reliever available (note that other forms of vitamin B do not have this effect). Side effects: gastric upset (which is easily prevented and relieved with antacids), reduced blood pressure and flushing of the skin (caused by vasodilation), and itchy sensation in the skin caused by histamine release.

Creatine - increases brain energy levels via ATP production.

Caffeine - improves concentration, idea production, but hinders memory encoding. Also produces the jitters. Caffeine is the most widely used psychoactive substance in the world.

Coffee - Bean. Contains caffeine; brewed coffee is high in antioxidants.

Rosemary - Herb. Rosemary has a very old, albeit unverified reputation for improving memory.

Vitamin C - Membrane stabilizer, involved in collagen synthesis. Strengthens neurons, making them less susceptible to damage. Vitamin C is also a co-factor in the brain's production of dopamine, and therefore it also has general nootropic effects.

Q10, the antoxidant


The antioxidant or free radical quenching properties of CoQ10 serve to greatly reduce oxidative damage to tissues as well as significantly inhibit the oxidation of LDL cholesterol (the bad guy, HDL cholesterol - the good guy) much more efficiently than vitamin E. This has great implications in the treatment of ischemia and reperfusion injury as well as the potential for slowing the development of atherosclerosis. In keeping with the free radical theory of aging, these antioxidant properties of CoQ10 have clear implications in the slowing of ageing and age related degenerative diseases. There is epidemiologic evidence in humans that uniformly shows a gradual decline in CoQ10 levels after the age of twenty.





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